Endocrine Abstracts

The aim of the present study was to determine the change of fasting serum leptin and insulin levels and insulin resistance in patients with risk factors of diabetes mellitus of type 2 (DM 2) including impaired glucose tolerance/impaired fasting glucose (IGT/IFG), obese and first-degree relatives of patients with diabetes after lifestyle modification.Material and methods: The study included 100 patients (32 men, 68 female) 25–65 years old at risk fac...

Aim: The aim of our study is to assess the efficacy of a lifestyle modification including altered diet composition and physical activity in preventing diabetes mellitus type 2 (DM 2) in individuals with impaired glucose tolerance and impaired fasting glucose (IGT/IFG) and influence it on changes serum leptin levelsMaterials and methods: The study included 327 patients with IGT/IFG (68 males and 258 females) 25–65 years. Patients were divided into tw...

Aims: The aim of our study is to assess the efficacy of lifestyle modification in preventing diabetes mellitus type 2 (DM 2)Materials and methods: The study included 100 patients (69 m 258 f) 25–65 years with impaired glucose tolerance/impaired fasting glucose (IGT/IFG) and newly diagnosed DM 2. Patients were divided into two groups matched by sex, age, weight, BMI, waist-to-hip ratio (WHR). Research group included 54 patients who received and carri...

Aim: The aim of our study is to assess the efficacy of a lifestyle modification including altered diet composition and physical activity in preventing diabetes mellitus type 2 (DM2) in individuals with impaired glucose tolerance and impaired fasting glucose (IGT/IFG) and influence it on changes serum leptin levels.Materials and methods: The study included 327 patients with IGT/IFG (68 m, 258 f) 25-65 years. Patients were divided into two groups matched b...

The aim of the present study was to determine the change of fasting serum leptin and insulin levels and insulin resistance in patients with risk factors of diabetes mellitus of type 2 (DM 2) including impaired glucose tolerance/impaired fasting glucose (IGT/IFG).Material and methods: The study included 100 patients (32 men, 68 female) 25–65 years old at risk factors of DM 2. All patients received recommendations on a balanced diet and physical activ...

Background: Diabetic nephropathy (DN) is a major cause of morbidity and mortality in type 1 diabetes (T1D) patients and associated with increased cardiovascular risk in type 2 diabetes (T2D) patients. Early detection of DN using neutrophil gelatinase-associated lipocalin (NGAL) assessment can help to reveal predisposed patients to its progression and to prevent progression of DN. Especially important it is in patients with normoalbuminuria.Aim: To determ...

Aims: The aim of our study is to assess the efficacy of lifestyle modification and picolinate chromium intake in preventing diabetes mellitus type 2 (DM 2)Materials and methods: The study included 100 patients (69 m 258 f) 25–65 years with impaired glucose tolerance (IGT) and newly diagnosed DM 2. Patients were divided into 2 groups matched by age, weight, body mass index (BMI), waist-to-hip ratio (WHR). Research group included 54 patients who carr...

Introduction: Preserving of C-peptide secretion in type 1 diabetes mellitus (DM1) is an important goal in treatment, as it provides the possibility of optimal compensation. Various approaches are used to achieve this goal. We initiated a study to assess the potential effect of the cell therapy based on autologous Tolerogenic Dendritic Cells on the newly diagnosed DM1 (NCT05207995, ClinicalTrials.gov).Methods: 4 patients who were injected with Tolerogenic...

Psoriasis patients have an increased risk of cardiovascular disease, stroke, hypertension, and type 2 diabetes (T2D). External factors (infections, stress, trauma, endocrine diseases) can trigger psoriasis. Skin diseases in patients with T2D are increased, hyperglycemia leads to damage to vascular intima. Itching of the skin leads to disruption of the repair and regeneration.Objective: To study the influence of T2D on the exacerbations of psoriasis.<...